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7 March 2023 Precision resection of soft tissue using picosecond laser pulses
Rainer J. Beck, Ioannis Bitharas, Katjana Ehrlich, Thomas I. Maisey, Ryan K. Mathew, Andrew J. Moore, James Moor, Robert R. Thomson, David G. Jayne, Jonathan D. Shephard
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Proceedings Volume PC12377, Optical Interactions with Tissue and Cells XXXIV; PC1237707 (2023) https://doi.org/10.1117/12.2650470
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
The successful laser ablation of clinically relevant tissue models by means of picosecond laser pulses is presented. This is a potential alternative to overcoming limitations of conventional tumour-surgery tools in terms of precision and thermal damage. The correlation of high-speed imaging of the ablation process, schlieren imaging of the resulting plume dynamics and a histopathological analysis of the post-process tissue morphology enables optimisation of the tissue removal rate whilst avoiding adverse cavitation effects. This facilitates minimal collateral thermal damage. Effective tissue removal is presented for the epithelial laser ablation of colonic tissue; with translation of this process towards infiltrating brain and head and neck cancer surgery further discussed.
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© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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Rainer J. Beck, Ioannis Bitharas, Katjana Ehrlich, Thomas I. Maisey, Ryan K. Mathew, Andrew J. Moore, James Moor, Robert R. Thomson, David G. Jayne, and Jonathan D. Shephard "Precision resection of soft tissue using picosecond laser pulses", Proc. SPIE PC12377, Optical Interactions with Tissue and Cells XXXIV, PC1237707 (7 March 2023); https://doi.org/10.1117/12.2650470
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KEYWORDS
Laser tissue interaction
Picosecond phenomena
Laser ablation
Tissues
Cancer
Colon
Surgery
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