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In this work, we demonstrate a fiber-based interferometric Diffuse Optical Spectroscopy (iDOS) approach to obtain quasi-concurrent information at early and late times of flight via a simple fiber optic switch. Time-of-flight (TOF) filtering is enabled by reducing the effective temporal coherence of the laser source, here achieved through rapid wavelength tuning. Early and late TOFs are alternatively interrogated by optical switches that select between reference paths with short and long time delays, respectively. This approach is used on a human forearm to obtain quasi-concurrent deep and superficial blood flow index at baseline and during occlusion.
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Santosh Aparanji, Mingjun Zhao, Vivek J. Srinivasan, "Interferometric diffusing wave spectroscopy with an optical time-of-flight switch," Proc. SPIE PC12378, Dynamics and Fluctuations in Biomedical Photonics XX, PC1237808 (7 March 2023); https://doi.org/10.1117/12.2650761