Breath compensated in vivo 3D whole-body imaging of small animals with mechanical scanning of a single-element transducer

Haeni Lee; Seongyi Han; Sinyoung Park; Seonghee Cho; Chulhong Kim; Jeesu Kim

doi:10.1117/12.2646100

27 March 2023 Breath compensated in vivo 3D whole-body imaging of small animals with mechanical scanning of a single-element transducer

Haeni Lee, Seongyi Han, Sinyoung Park, Seonghee Cho, Chulhong Kim, Jeesu Kim

Author Affiliations +

Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC123792I (2023) https://doi.org/10.1117/12.2646100
Event: SPIE BiOS, 2023, San Francisco, California, United States

Conference Poster

Abstract

In photoacoustic images with mechanical scanning of single-element ultrasound transducers, respiratory movements generate distortion in data due to slow imaging speed. To overcome this technical issue, we propose an ultrasound-guided breath-compensation method for volumetric photoacoustic data. We have successfully corrected the breath-related distortion by using simultaneously acquired ultrasound data. The resulting three-dimensional photoacoustic images can visualize volumetric hemoglobin oxygen saturation map in the whole body of mice. We believe that these results can provide a more accurate analytical perspective for biomedical imaging studies.

Citation Download Citation

Haeni Lee, Seongyi Han, Sinyoung Park, Seonghee Cho, Chulhong Kim, and Jeesu Kim "Breath compensated in vivo 3D whole-body imaging of small animals with mechanical scanning of a single-element transducer", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123792I (27 March 2023); https://doi.org/10.1117/12.2646100

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