15 March 2023Overcoming the spatial and temporal coherence limitations of reverberant elastography in raster-scanned OCT systems (Conference Presentation)
1Wellman Ctr. for Photomedicine (United States) 2Institute for Medical Engineering & Science (United States) 3Massachusetts Institute of Technology (United States)
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OCT has enabled high resolution imaging of the subsurface microstructure of tissues. However, existing systems lack the ability to robustly measure biomechanical contrast. To image stiffness, reverberant elastography uses correlations of the velocity field and curve fitting to their expected functional shape to measure shear wave number. Prior work has assumed that raster scan systems cannot achieve spatial coherence, so current methods require reproducible synchronization of the excitation with imaging. We demonstrate through simulation and phantom imaging that spatial coherence does indeed exist within a single B-scan. Furthermore, leveraging the displacement field also allows us to overcome temporal coherence limitations.
Ginger J. Schmidt,Taylor M. Cannon,Brett E. Bouma, andNéstor Uribe-Patarroyo
"Overcoming the spatial and temporal coherence limitations of reverberant elastography in raster-scanned OCT systems (Conference Presentation)", Proc. SPIE PC12381, Optical Elastography and Tissue Biomechanics X, PC123810Q (15 March 2023); https://doi.org/10.1117/12.2654326
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Ginger J. Schmidt, Taylor M. Cannon, Brett E. Bouma, Néstor Uribe-Patarroyo, "Overcoming the spatial and temporal coherence limitations of reverberant elastography in raster-scanned OCT systems (Conference Presentation)," Proc. SPIE PC12381, Optical Elastography and Tissue Biomechanics X, PC123810Q (15 March 2023); https://doi.org/10.1117/12.2654326