Anne van Klinken,1 Ruud Jansen,1 Arthur Hendriks,1 Chenhui Li,1 Mathias Dolci,1 Petar Sevo,1 Luca Picelli,1 Mildred S. Cano-Velázquezhttps://orcid.org/0000-0002-9128-0161,1 Peter Zijlstra,1 Andrea Fiore1
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We demonstrate a compact interrogation method for resonance-based biosensors, based on an integrated photonic chip with an array of resonant-cavity enhanced photodetectors. Due to the high signal-to-noise ratio, wavelength shifts in the 10 pm range can be measured, orders of magnitude smaller than the sensor and interrogator linewidths. This approach allows the read-out of resonance-based optical biosensors with simple integrated components, potentially enabling compact and low-cost sensing systems for point-of-care diagnostics.
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Anne van Klinken, Ruud Jansen, Arthur Hendriks, Chenhui Li, Mathias Dolci, Petar Sevo, Luca Picelli, Mildred S. Cano-Velázquez, Peter Zijlstra, Andrea Fiore, "Integrated spectral interrogator for point-of-care biosensors," Proc. SPIE PC12387, Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics, PC123870B (30 March 2023); https://doi.org/10.1117/12.2649821