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17 March 2023 Broadband mid-infrared milk protein analysis based on quantum cascade technology
Borislav Hinkov, Alicja Dabrowska, Mauro David, Andreas Schwaighofer, Stephan Freitag, Aaron M. Andrews, Gottfried Strasser, Bernhard Lendl
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Proceedings Volume PC12430, Quantum Sensing and Nano Electronics and Photonics XIX; PC124300E (2023) https://doi.org/10.1117/12.2650801
Event: SPIE OPTO, 2023, San Francisco, California, United States
Abstract
Mid-infrared chemical sensors based on quantum cascade (QC) devices offer improved sensitivity, portability and costs compared to FTIR-based spectrometers. In this work, we combine for the first time a broadband external-cavity QC laser (EC-QCL) with a spectrally tailored QC detector (QCD) for broadband detection of bovine milk proteins including β-lactoglobulin, α-lactalbumin and casein. We analyze concentrations between 0.25-15 g/L in a 12.5-µm transmission flow cell in the amide-I and -II band (~1730-1470 cm-1) and obtain: a RMS noise-level of 0.067 mAU, a limit-of-detection of ~0.09 g/L, excellent agreement with FTIR absorbance-spectra and similar performance as much more bulky high-end FTIR-spectrometers.
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Borislav Hinkov, Alicja Dabrowska, Mauro David, Andreas Schwaighofer, Stephan Freitag, Aaron M. Andrews, Gottfried Strasser, and Bernhard Lendl "Broadband mid-infrared milk protein analysis based on quantum cascade technology", Proc. SPIE PC12430, Quantum Sensing and Nano Electronics and Photonics XIX, PC124300E (17 March 2023); https://doi.org/10.1117/12.2650801
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KEYWORDS
Mid-IR
Proteins
Spectrometers
FT-IR spectroscopy
Liquids
Spectroscopy
Quantum cascade lasers
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