Optical coherence tomography (OCT) and speckle imaging are two coherence-based imaging modalities with burgeoning applications in rapid non-invasive measurement of the skin. Both modalities are sensitive to tissue morphology and have polarization-sensitive augmentations. This study compares Polarization Sensitive OCT (PS-OCT) and Polarization Speckle measurements to better understand the relationship between polarization and coherence properties of skin. Volunteers of Fitzpatrick skin type I through VI were recruited and healthy skin was measured at four body sites (palm, inner forearm, forehead, and eye corner). Preliminary results indicate a strong similarity between the skin surface roughness measurements of PS-OCT and polarization speckle. In regards to tissue depolarization, PS-OCT measurements appear minimally affected by skin color, whereas polarization speckle was strongly affected due to differing measurement wavelengths. Among body sites, the palm and face were found to be generally smoother than the forearm; however the epidermis layer of the palm demonstrated notably greater polarization scrambling.
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