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Within 24 hours post treatment, photodynamic therapy causes a drastic reduction in tumor oxygenation and an increase in ultrasound scattering. While these trends can lead to determining acute tumor response, monitoring vascular and structural dynamics through 72 hours post treatment using ultrasound guided photoacoustic imaging provides a better insight on long-term PDT outcomes.
Skye Edwards andSrivalleesha Mallidi
"Quantitative ultrasound and photoacoustic imaging to monitor photodynamic therapy outcomes", Proc. SPIE PC12823, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXII, PC128230C (13 March 2024); https://doi.org/10.1117/12.3003464
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Skye Edwards, Srivalleesha Mallidi, "Quantitative ultrasound and photoacoustic imaging to monitor photodynamic therapy outcomes," Proc. SPIE PC12823, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXII, PC128230C (13 March 2024); https://doi.org/10.1117/12.3003464