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8 April 2024 Transient blood flow changes in the human retina in response to flicker stimulation measured with a combined OCT+ERG system
Khushmeet Kaur Dhaliwal, James Simmons, Alex Wong, Chris Hudson, Nadine Furtado, Tom Wright, Brian Ballios, Kostadinka Bizheva
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Proceedings Volume PC12824, Ophthalmic Technologies XXXIV; PC128240L (2024) https://doi.org/10.1117/12.3001798
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Visual stimulation-induced increase in the metabolic activity of retinal neurons leads to temporary vasodilation of retinal blood vessels and an increase in the retinal blood flow, which is often referred to as functional hyperaemia. Neurodegenerative retinal diseases such as glaucoma, age-related macular degeneration, and diabetic retinopathy have been known to cause progressive damage to the retinal morphology, blood perfusion and retinal blood flow, and eventually lead to blindness. In this study, we utilize a combined OCT+ERG system to investigate functional hyperemia in the human retina.
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Khushmeet Kaur Dhaliwal, James Simmons, Alex Wong, Chris Hudson, Nadine Furtado, Tom Wright, Brian Ballios, and Kostadinka Bizheva "Transient blood flow changes in the human retina in response to flicker stimulation measured with a combined OCT+ERG system", Proc. SPIE PC12824, Ophthalmic Technologies XXXIV, PC128240L (8 April 2024); https://doi.org/10.1117/12.3001798
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KEYWORDS
Blood circulation
Optical coherence tomography
Retina
Visualization
Data acquisition
Doppler effect
Frequency response
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