Reconstructing the entire anterior and posterior chamber of the eye montaging volumes from visible-light optical coherence tomography

Daniel S. Kim; Raymond Fang; Hao F. Zhang; Cheng Sun

doi:10.1117/12.3005731

13 March 2024 Reconstructing the entire anterior and posterior chamber of the eye montaging volumes from visible-light optical coherence tomography

Daniel S. Kim, Raymond Fang, Hao F. Zhang, Cheng Sun

Author Affiliations +

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC128302E (2024) https://doi.org/10.1117/12.3005731
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Owing to its high axial resolution, optical coherence tomography (OCT) has the capacity to reconstruct 3-D structures with micron precision. However, due to tissue scattering, limited field-of-view per scan, and limited depth of focus, it is challenging to reconstruct large, complex volumetric objects that do not fit within one OCT scan. To address this problem, we developed novel montaging schemes to combine OCT volumes acquired from different angles and positions. We demonstrate the effectiveness of this method by measuring the aqueous volume of the anterior and posterior chambers of the mouse eye.

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(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

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Daniel S. Kim, Raymond Fang, Hao F. Zhang, and Cheng Sun "Reconstructing the entire anterior and posterior chamber of the eye montaging volumes from visible-light optical coherence tomography", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC128302E (13 March 2024); https://doi.org/10.1117/12.3005731

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KEYWORDS

Optical coherence tomography

Vacuum chambers

Eye

Image segmentation

Eye models

In vivo imaging

Interpolation

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