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13 March 2024 Real time cavitation mapping to guide photo-mediated ultrasound therapy with functional OCT
Yuchen Song, Shuang Wei, Zhongping Chen
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Proceedings Volume PC12840, Optical Interactions with Tissue and Cells XXXV; PC128400F (2024) https://doi.org/10.1117/12.3003315
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Photo-mediate ultrasound therapy (PUT) is a new anti-vascular technique based on cavitation induced spallation, applies nanosecond laser pulses and ultrasound bursts simultaneously to promote cavitation activity to remove the blood vessel. However, the real time detection of cavitation to guide PUT in real time is still challenging. To better understand the spatial-temporal distribution of cavitation bubbles, we proposed to integrate Doppler optical coherence tomography (DOCT) combined PUT, where the DOCT was used to visualize shockwave-induced cavitation and monitor treatment response in real time. The addition of DOCT to PUT allows for quantitative prescreening and real time monitoring during treatment response, which can improve the safety and effectiveness of the therapy.
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Yuchen Song, Shuang Wei, and Zhongping Chen "Real time cavitation mapping to guide photo-mediated ultrasound therapy with functional OCT", Proc. SPIE PC12840, Optical Interactions with Tissue and Cells XXXV, PC128400F (13 March 2024); https://doi.org/10.1117/12.3003315
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KEYWORDS
Laser therapeutics
Ultrasonography
Ultrasound transducers
Signal detection
Infrared cameras
Laser frequency
Nanosecond lasers
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