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Cell growth is very important for the development and maintenance of organisms, and it is essential to study factors that affect cell growth, such as gas concentrations that affect cell metabolism, especially oxygen and carbon dioxide. In this study, the dynamic activity of cells according to oxygen concentration was analyzed using a dynamic full-field optical coherence tomography imaging system in a gas-controlled chamber for label-free analysis of living cells. This study aims to understand the relationship between gas supply levels and intracellular activity through non-invasive observation. This discovery could have important implications for biomedicine and biotechnology.
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Soongho Park, Varun Gunda, Thien Nguyen, Jinho Park, Amir Gandjbakhche, "Observing the influence of gas concentration in intracellular dynamic activity using label-free optical imaging," Proc. SPIE PC12840, Optical Interactions with Tissue and Cells XXXV, PC128400I (13 March 2024); https://doi.org/10.1117/12.3001123