Automatic photoacoustic and ultrasound Doppler imaging of human hand rheumatoid arthritis: a longitudinal study

Xiaorui Peng; Grigorios Karageorgos; Jianwei Qiu; Soumya Ghose; Zhanpeng Xu; Zhaoyuan Yang; Aaron Dentinger; Siddarth Ragupathi; Janggun Jo; Nada Abdulaziz; Girish Gandikota; Guan Xu; David Mills; Xueding Wang

doi:10.1117/12.3000365

13 March 2024 Automatic photoacoustic and ultrasound Doppler imaging of human hand rheumatoid arthritis: a longitudinal study

Xiaorui Peng, Grigorios Karageorgos, Jianwei Qiu, Soumya Ghose, Zhanpeng Xu, Zhaoyuan Yang, Aaron Dentinger, Siddarth Ragupathi, Janggun Jo, Nada Abdulaziz, Girish Gandikota, Guan Xu, David Mills, Xueding Wang

Author Affiliations +

Proceedings Volume PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024; PC1284203 (2024) https://doi.org/10.1117/12.3000365
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

A longitudinal study on both 3D and 2D photoacoustic and Doppler ultrasound imaging of human hand rheumatoid arthritis progression has been performed using an automatic imaging system based on GEHC VividTM E95 with L8-18i-D probe and OPOTEK tunable laser system. Bi-weekly imaging has been performed starting from baseline (before patients start medication). Both photoacoustic and Doppler ultrasound can confirm the disease development, however, photoacoustic has higher correlation coefficients (with a median of 78.9%, p = 0.039) with patients’ PGA score.

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Xiaorui Peng, Grigorios Karageorgos, Jianwei Qiu, Soumya Ghose, Zhanpeng Xu, Zhaoyuan Yang, Aaron Dentinger, Siddarth Ragupathi, Janggun Jo, Nada Abdulaziz, Girish Gandikota, Guan Xu, David Mills, and Xueding Wang "Automatic photoacoustic and ultrasound Doppler imaging of human hand rheumatoid arthritis: a longitudinal study", Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC1284203 (13 March 2024); https://doi.org/10.1117/12.3000365

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