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13 March 2024 Video-rate endocavity photoacoustic ultrasound imaging with a miniaturized light delivery
Donghyeon Oh, Hyunhee Kim, Chulhong Kim
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Proceedings Volume PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024; PC128420G (2024) https://doi.org/10.1117/12.3000746
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Endocavity ultrasound (US) imaging is commonly used in gynecology and urology to diagnose challenging genital diseases. The convergence of photoacoustic (PA) imaging with clinical US imaging is actively explored in research due to their compatibility. However, the physical size of the laser delivery unit limits its insertion into confined vaginal or rectal canals. In our study, we performed video-rate endocavity PAUS imaging using a miniaturized probe. This achieved a fine radial resolution of 277 μm and 341 μm, and angular resolution of 1.52° and 1.23°. Multispectral PA imaging allowed quantification of a methylene blue (MB)/indocyanine green (ICG) cocktail ratio. The fast temporal resolution captured ICG infusion kinetics in ex vivo porcine ovary. Finally, we noninvasively imaged the male rat's reproductive system, confirming prostate vessel pulsation via PA and US imaging.
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Donghyeon Oh, Hyunhee Kim, and Chulhong Kim "Video-rate endocavity photoacoustic ultrasound imaging with a miniaturized light delivery", Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC128420G (13 March 2024); https://doi.org/10.1117/12.3000746
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KEYWORDS
Miniaturization
Photoacoustic spectroscopy
Ultrasonography
Photoacoustic imaging
Multispectral imaging
Spatial resolution
Reproductive system
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