A new-generation FACED imaging solution using diffractive optical elements

Zhou Jiang; Kelvin Chak Man Lee; Kevin Kin Man Tsia

doi:10.1117/12.3009053

13 March 2024 A new-generation FACED imaging solution using diffractive optical elements

Zhou Jiang, Kelvin Chak Man Lee, Kevin Kin Man Tsia

Proceedings Volume PC12853, High-Speed Biomedical Imaging and Spectroscopy IX; PC128530E (2024) https://doi.org/10.1117/12.3009053
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Free-space angular-chirp-enhanced delay (FACED) imaging is proven to offer ultrafast imaging speed needed in a wide range of bioimaging applications. However, this superior performance critically requires stringent hardware mechanical stability, which limits it wide applicability for robust long-term operation. We develop FACED 2.0, that integrates diffractive optical elements with the infinity mirrors for preserving the capability of high-density laser-scanning foci generation, and more importantly, and enabling extended stable continuous operation over days or even a week. As a proof-of-concept demonstration, we showcased the applicability of FACED 2.0 in high-throughput imaging flow cytometry at the throughput equivalent to ~10,000 cells/sec.

Conference Presentation

Citation Download Citation

Zhou Jiang, Kelvin Chak Man Lee, and Kevin Kin Man Tsia "A new-generation FACED imaging solution using diffractive optical elements", Proc. SPIE PC12853, High-Speed Biomedical Imaging and Spectroscopy IX, PC128530E (13 March 2024); https://doi.org/10.1117/12.3009053

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