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We generalize the concept of optimally chiral light (OCL), which encompasses all fields with maximum chirality at a given energy density, such as circularly polarized light (CPL), to light in an isotropic medium, where the optical chirality is not well defined. We find the generalized optimal chirality condition by enforcing the constructive scattering of the chiral response of chiral molecules with the phase shift between the incident electric and magnetic fields. The generalized OCL displays powerful electric-magnetic symmetries that maximize chiral light-matter interactions with simplified expressions.
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