SERS-based detection of biomolecules in complex biological matrices

Dana Cialla-May; Juergen Popp

doi:10.1117/12.3022287

20 June 2024 SERS-based detection of biomolecules in complex biological matrices

Dana Cialla-May, Juergen Popp

Proceedings Volume PC13008, Biophotonics in Point-of-Care III; PC1300805 (2024) https://doi.org/10.1117/12.3022287
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

We present the SERS-based detection of biomolecules in complex biological matrices. This includes the detection of co-factors in bacterial membranes, drugs and its metabolites in clinically relevant matrices as well as cancer-relevant marker in saliva. To overcome the complexity of the biological matrix, a high affinity of the target analyte is essential, which is improved by sample preparation processes or specific enrichment on the sensor surface.

Conference Presentation

Citation Download Citation

Dana Cialla-May and Juergen Popp "SERS-based detection of biomolecules in complex biological matrices", Proc. SPIE PC13008, Biophotonics in Point-of-Care III, PC1300805 (20 June 2024); https://doi.org/10.1117/12.3022287

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