Compact portable ocular microtremor sensor: design, development and calibration

James Patrick Ryle; Mohammed Ali Al-Kalbani; Niamh Collins; Unnikrishnan Gopinathan; Gerard Boyle; Davis Coakley; John T. Sheridan

doi:10.1117/1.3083435

1 January 2009 Compact portable ocular microtremor sensor: design, development and calibration

James Patrick Ryle, Mohammed Ali Al-Kalbani, Niamh Collins, Unnikrishnan Gopinathan, Gerard Boyle, Davis Coakley, John T. Sheridan

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Journal of Biomedical Optics, Vol. 14, Issue 1, 014021 (January 2009). https://doi.org/10.1117/1.3083435

Abstract

Ocular microtremor (OMT) is a physiological high-frequency (up to 150 Hz) low-amplitude (25–2500 nm peak-to-peak) involuntary motion of the human eye. Recent studies suggest a number of clinical applications for OMT that include monitoring the depth of anesthesia of a patient in surgery, prediction of outcome in coma, and diagnosis of brain stem death. Clinical OMT investigations to date have used mechanical piezoelectric probes or piezoelectric strain gauges that have many drawbacks which arise from the fact that the probe is in contact with the eye. We describe the design of a compact noncontact sensing device to measure OMT that addresses some of the above drawbacks. We evaluate the system performance using a calibrated piezoelectric vibrator that simulates OMT signals under conditions that can occur in practice, i.e., wet eye conditions. We also test the device at low light levels well within the eye safety range.

©(2009) Society of Photo-Optical Instrumentation Engineers (SPIE)

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James Patrick Ryle, Mohammed Ali Al-Kalbani, Niamh Collins, Unnikrishnan Gopinathan, Gerard Boyle, Davis Coakley, and John T. Sheridan "Compact portable ocular microtremor sensor: design, development and calibration," Journal of Biomedical Optics 14(1), 014021 (1 January 2009). https://doi.org/10.1117/1.3083435

Published: 1 January 2009

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