Photoacoustic tomography of the mouse cerebral cortex with a high-numerical-aperture-based virtual point detector

Changhui Li; Lihong V. Wang

doi:10.1117/1.3122365

1 March 2009 Photoacoustic tomography of the mouse cerebral cortex with a high-numerical-aperture-based virtual point detector

Changhui Li, Lihong V. Wang

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Journal of Biomedical Optics, Vol. 14, Issue 2, 024047 (March 2009). https://doi.org/10.1117/1.3122365

Abstract

The mouse cerebral cortex was imaged in situ by photoacoustic tomography (PAT). Instead of a flat ultrasonic transducer, a virtual point detector based on a high numerical aperture (NA), positively focused transducer was used. This virtual point detector has a wide omnidirectional acceptance angle, a high sensitivity, and a negligible aperture effect. In addition, the virtual point detector can be located much more closely to the object during the detection. Compared with a finite-size flat transducer, images generated by using this virtual point detector have both uniform signal-to-noise ratio (SNR) and resolution.

©(2009) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Changhui Li and Lihong V. Wang "Photoacoustic tomography of the mouse cerebral cortex with a high-numerical-aperture-based virtual point detector," Journal of Biomedical Optics 14(2), 024047 (1 March 2009). https://doi.org/10.1117/1.3122365

Published: 1 March 2009

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