Photoacoustic microscopy with 2-µm transverse resolution

Geng Ku; Konstantin I. Maslov; Li Li; Lihong V. Wang

doi:10.1117/1.3339912

1 March 2010 Photoacoustic microscopy with 2-μm transverse resolution

Geng Ku, Konstantin I. Maslov, Li Li, Lihong V. Wang

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Journal of Biomedical Optics, Vol. 15, Issue 2, 021302 (March 2010). https://doi.org/10.1117/1.3339912

Abstract

We present a new-generation optical-resolution confocal photoacoustic microscope, consisting of a 0.25-numerical aperture optical microscope objective and a 75-MHz center-frequency spherically focused ultrasonic transducer. Experiments verified that this microscope has a transverse resolution of 2 μm, which is the highest to our knowledge among all photoacoustic imaging systems. In situ imaging of mouse ears shows the feasibility of resolving individual red blood cells in microvessels using the current system.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Geng Ku, Konstantin I. Maslov, Li Li, and Lihong V. Wang "Photoacoustic microscopy with 2-μm transverse resolution," Journal of Biomedical Optics 15(2), 021302 (1 March 2010). https://doi.org/10.1117/1.3339912

Published: 1 March 2010

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