Saturation effect in functional photoacoustic imaging

Jing Wang; Tan Liu; Shuliang Jiao; Ruimin Chen; Qifa Zhou; K. Kirk Shung; Lihong V. Wang; Hao F. Zhang

doi:10.1117/1.3333549

1 March 2010 Saturation effect in functional photoacoustic imaging

Jing Wang, Tan Liu, Shuliang Jiao, Ruimin Chen, Qifa Zhou, K. Kirk Shung, Lihong V. Wang, Hao F. Zhang

Author Affiliations +

Journal of Biomedical Optics, Vol. 15, Issue 2, 021317 (March 2010). https://doi.org/10.1117/1.3333549

Abstract

We investigate the saturation effect, which describes the violation of the linearity between the measured photoacoustic amplitude and the object's optical absorption coefficient in functional photoacoustic imaging when the optical absorption in the object increases. We model the optical energy deposition and photoacoustic signal generation and detection in a semi-infinite optical absorbing object. Experiments are carried out by measuring photoacoustic signals generated from an ink-filled plastic tube. The saturation effect is studied by varying the optical absorption coefficient in the model and the ink concentration in the photoacoustic experiments. By changing the center frequency of the ultrasonic detector, the requirement to minimize the saturation effect in functional photoacoustic imaging is established.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Jing Wang, Tan Liu, Shuliang Jiao, Ruimin Chen, Qifa Zhou, K. Kirk Shung, Lihong V. Wang, and Hao F. Zhang "Saturation effect in functional photoacoustic imaging," Journal of Biomedical Optics 15(2), 021317 (1 March 2010). https://doi.org/10.1117/1.3333549

Published: 1 March 2010

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KEYWORDS

Signal detection

Ultrasonics

Absorption

Sensors

Photoacoustic imaging

Photoacoustic spectroscopy

Signal generators

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