Identification of the optimal wavelengths for optical topography: a photon measurement density function analysis

Teresa M. Correia; Adam P. Gibson; Jeremy C. Hebden

doi:10.1117/1.3484747

1 September 2010 Identification of the optimal wavelengths for optical topography: a photon measurement density function analysis

Teresa M. Correia, Adam P. Gibson, Jeremy C. Hebden

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Journal of Biomedical Optics, Vol. 15, Issue 5, 056002 (September 2010). https://doi.org/10.1117/1.3484747

Abstract

A method is presented to select the optimal wavelengths for multispectral optical topography, which not only gives good separation between chromophores, absorption, and scattering, but also minimizes the differences between interrogated volumes. This method uses the sum of squared differences to compare photon measurement density functions, which were generated for wavelengths in the near-infrared (NIR) range for a suitable model of tissue optical properties. It is found that including this condition significantly influences the range of optimal wavelengths. However, for the adult human head, the differences between interrogated volumes at NIR wavelengths are very small and image reconstruction is only slightly improved when measurements with overlapping sensitivities are used.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Teresa M. Correia, Adam P. Gibson, and Jeremy C. Hebden "Identification of the optimal wavelengths for optical topography: a photon measurement density function analysis," Journal of Biomedical Optics 15(5), 056002 (1 September 2010). https://doi.org/10.1117/1.3484747

Published: 1 September 2010

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