Photoinduced cell morphology alterations quantified within adipose tissues by spectral optical coherence tomography

Irina Yu. Yanina; Natalia A. Trunina; Valery V. Tuchin

doi:10.1117/1.JBO.18.11.111407

2 August 2013 Photoinduced cell morphology alterations quantified within adipose tissues by spectral optical coherence tomography

Irina Yu. Yanina, Natalia A. Trunina, Valery V. Tuchin

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Journal of Biomedical Optics, Vol. 18, Issue 11, 111407 (August 2013). https://doi.org/10.1117/1.JBO.18.11.111407

Abstract

Morphological changes of the adipose tissue at phototreatment are studied in vitro using optical coherence tomography. The 200 to 600 μm fat tissue slices are used in the experiments. The observed change in the tissue structure was associated with fat cell lipolysis and destruction caused by the photodynamic effect. It is found that overall heating of a sample from room to physiological temperature leads to deeper and faster morphology tissue changes if other processing conditions are kept constant. These data support the hypothesis that photodynamic/photothermal treatment induces fat cell lipolysis during some period after treatment.

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Irina Yu. Yanina, Natalia A. Trunina, and Valery V. Tuchin "Photoinduced cell morphology alterations quantified within adipose tissues by spectral optical coherence tomography," Journal of Biomedical Optics 18(11), 111407 (2 August 2013). https://doi.org/10.1117/1.JBO.18.11.111407

Published: 2 August 2013

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