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21 August 2014 Microcirculatory changes identified by photoacoustic microscopy in patients with complex regional pain syndrome type I after stellate ganglion blocks
Yong Zhou, Xiaobin Yi, Wenxin Xing, Song Hu, Konstantin I. Maslov, Lihong V. Wang
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Journal of Biomedical Optics, Vol. 19, Issue 8, 086017 (August 2014). https://doi.org/10.1117/1.JBO.19.8.086017
Abstract
Complex regional pain syndrome (CRPS) is a chronic pain syndrome that causes intractable pain, disability, and poor quality of life for patients. The etiology and pathophysiology of CRPS are still poorly understood. Due to a lack of proper diagnostic tools, the prognosis of CRPS is primarily based on clinical observation. The objective of this work is to evaluate a new imaging modality, photoacoustic microscopy (PAM), for assisting diagnoses and monitoring the progress and treatment outcome of CRPS. Blood vasculature and oxygen saturation (sO 2 ) were imaged by PAM from eight adult patients with CRPS-1. Patients’ hands and cuticles were imaged both before and after stellate ganglion block (SGB) for comparison. For all patients, both vascular structure and sO 2 could be assessed by PAM. In addition, more vessels and stronger signals were observed after SGB. The results show that PAM can help diagnose and monitor CRPS.
© 2014 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2014/$25.00 © 2014 SPIE
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Yong Zhou, Xiaobin Yi, Wenxin Xing, Song Hu, Konstantin I. Maslov, and Lihong V. Wang "Microcirculatory changes identified by photoacoustic microscopy in patients with complex regional pain syndrome type I after stellate ganglion blocks," Journal of Biomedical Optics 19(8), 086017 (21 August 2014). https://doi.org/10.1117/1.JBO.19.8.086017
Published: 21 August 2014
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KEYWORDS
Blood
Photoacoustic microscopy
Diagnostics
Oxygen
Blood circulation
Tissues
Acoustics
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