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29 December 2015 Adjunctive dental therapy via tooth plaque reduction and gingivitis treatment by blue light-emitting diodes tooth brushing
Elina A. Genina, Vladimir A. Titorenko, Andrey V. Belikov, Alexey N. Bashkatov, Valery V. Tuchin
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Journal of Biomedical Optics, Vol. 20, Issue 12, 128004 (December 2015). https://doi.org/10.1117/1.JBO.20.12.128004
Abstract
The efficacy of blue light-emitting toothbrushes (B-LETBs) (405 to 420 nm, power density 2  mW/cm2) for reduction of dental plaques and gingival inflammation has been evaluated. Microbiological study has shown the multifactor therapeutic action of the B-LETBs on oral pathological microflora: in addition to partial mechanical removal of bacteria, photodynamic action suppresses them up to 97.5%. In the pilot clinical studies, subjects with mild to moderate gingivitis have been randomly divided into two groups: a treatment group that used the B-LETBs and a control group that used standard toothbrushes. Indices of plaque, gingival bleeding, and inflammation have been evaluated. A significant improvement of all dental indices in comparison with the baseline (by 59%, 66%, and 82% for plaque, gingival bleeding, and inflammation, respectively) has been found. The treatment group has demonstrated up to 50% improvement relative to the control group. We have proposed the B-LETBs to serve for prevention of gingivitis or as an alternative to conventional antibiotic treatment of this disease due to their effectiveness and the absence of drug side effects and bacterial resistance.
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2015/$25.00 © 2015 SPIE
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Elina A. Genina, Vladimir A. Titorenko, Andrey V. Belikov, Alexey N. Bashkatov, and Valery V. Tuchin "Adjunctive dental therapy via tooth plaque reduction and gingivitis treatment by blue light-emitting diodes tooth brushing," Journal of Biomedical Optics 20(12), 128004 (29 December 2015). https://doi.org/10.1117/1.JBO.20.12.128004
Published: 29 December 2015
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Cited by 20 scholarly publications and 1 patent.
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KEYWORDS
Teeth
Inflammation
Bacteria
Photodynamic therapy
Light emitting diodes
Blue light emitting diodes
Biomedical optics
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