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17 April 2015 Measurements of fundamental properties of homogeneous tissue phantoms
Maciej S. Wróbel, Alexey P. Popov, Alexander V. Bykov, Matti Kinnunen, Malgorzata Jędrzejewska-Szczerska, Valery V. Tuchin
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Journal of Biomedical Optics, Vol. 20, Issue 4, 045004 (April 2015). https://doi.org/10.1117/1.JBO.20.4.045004
Abstract
We present the optical measurement techniques used in human skin phantom studies. Their accuracy and the sources of errors in microscopic parameters’ estimation of the produced phantoms are described. We have produced optical phantoms for the purpose of simulating human skin tissue at the wavelength of 930 nm. Optical coherence tomography was used to measure the thickness and surface roughness and to detect the internal inhomogeneities. A more detailed study of phantom surface roughness was carried out with the optical profilometer. Reflectance, transmittance, and collimated transmittance of phantoms were measured using an integrating-sphere spectrometer setup. The scattering and absorption coefficients were calculated with the inverse adding-doubling method. The reduced scattering coefficient at 930 nm was found to be 1.57±0.14  mm−1 and the absorption was 0.22±0.03  mm−1. The retrieved optical properties of phantoms are in agreement with the data found in the literature for real human tissues.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
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Maciej S. Wróbel, Alexey P. Popov, Alexander V. Bykov, Matti Kinnunen, Malgorzata Jędrzejewska-Szczerska, and Valery V. Tuchin "Measurements of fundamental properties of homogeneous tissue phantoms," Journal of Biomedical Optics 20(4), 045004 (17 April 2015). https://doi.org/10.1117/1.JBO.20.4.045004
Published: 17 April 2015
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KEYWORDS
Scattering
Transmittance
Reflectivity
Absorption
Tissue optics
Optical properties
Collimation
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