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2 January 2018 Quantitative photoacoustic imaging of two-photon absorption
Patrick Bardsley, Kui Ren, Rongting Zhang
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Journal of Biomedical Optics, Vol. 23, Issue 1, 016002 (January 2018). https://doi.org/10.1117/1.JBO.23.1.016002
Abstract
Photoacoustic tomography (PAT) is a hybrid imaging modality where we intend to reconstruct optical properties of heterogeneous media from measured ultrasound signals generated by the photoacoustic effect. In recent years, there have been considerable interests in using PAT to image two-photon absorption, in addition to the usual single-photon absorption, inside diffusive media. We present a mathematical model for quantitative image reconstruction in two-photon photoacoustic tomography (TP-PAT). We propose a computational strategy for the reconstruction of the optical absorption coefficients and provide some numerical evidences based on synthetic photoacoustic acoustic data to demonstrate the feasibility of quantitative reconstructions in TP-PAT.
© 2018 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2018/$25.00 © 2018 SPIE
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Patrick Bardsley, Kui Ren, and Rongting Zhang "Quantitative photoacoustic imaging of two-photon absorption," Journal of Biomedical Optics 23(1), 016002 (2 January 2018). https://doi.org/10.1117/1.JBO.23.1.016002
Received: 5 July 2017; Accepted: 5 December 2017; Published: 2 January 2018
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Cited by 11 scholarly publications and 1 patent.
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KEYWORDS
Absorption
Reconstruction algorithms
Diffusion
Ultrasonography
Acquisition tracking and pointing
Photoacoustic imaging
Acoustics
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