Measurement of tissue optical properties in the context of tissue optical clearing

Alexey N. Bashkatov; Kirill V. Berezin; Konstantin N. Dvoretskiy; Maria L. Chernavina; Elina A. Genina; Vadim D. Genin; Vyacheslav I. Kochubey; Ekaterina N. Lazareva; Alexander B. Pravdin; Marina E. Shvachkina; Polina A. Timoshina; Daria K. Tuchina; Dmitry D. Yakovlev; Dmitry A. Yakovlev; Irina Yu Yanina; Olga S. Zhernovaya; Valery V. Tuchin

doi:10.1117/1.JBO.23.9.091416

23 August 2018 Measurement of tissue optical properties in the context of tissue optical clearing

Alexey N. Bashkatov, Kirill V. Berezin, Konstantin N. Dvoretskiy, Maria L. Chernavina, Elina A. Genina, Vadim D. Genin, Vyacheslav I. Kochubey, Ekaterina N. Lazareva, Alexander B. Pravdin, Marina E. Shvachkina, Polina A. Timoshina, Daria K. Tuchina, Dmitry D. Yakovlev, Dmitry A. Yakovlev, Irina Yu Yanina, Olga S. Zhernovaya, Valery V. Tuchin

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Journal of Biomedical Optics, Vol. 23, Issue 9, 091416 (August 2018). https://doi.org/10.1117/1.JBO.23.9.091416

Abstract

Nowadays, dynamically developing optical (photonic) technologies play an ever-increasing role in medicine. Their adequate and effective implementation in diagnostics, surgery, and therapy needs reliable data on optical properties of human tissues, including skin. This paper presents an overview of recent results on the measurements and control of tissue optical properties. The issues reported comprise a brief review of optical properties of biological tissues and efficacy of optical clearing (OC) method in application to monitoring of diabetic complications and visualization of blood vessels and microcirculation using a number of optical imaging technologies, including spectroscopic, optical coherence tomography, and polarization- and speckle-based ones. Molecular modeling of immersion OC of skin and specific technique of OC of adipose tissue by its heating and photodynamic treatment are also discussed.

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Alexey N. Bashkatov, Kirill V. Berezin, Konstantin N. Dvoretskiy, Maria L. Chernavina, Elina A. Genina, Vadim D. Genin, Vyacheslav I. Kochubey, Ekaterina N. Lazareva, Alexander B. Pravdin, Marina E. Shvachkina, Polina A. Timoshina, Daria K. Tuchina, Dmitry D. Yakovlev, Dmitry A. Yakovlev, Irina Yu Yanina, Olga S. Zhernovaya, and Valery V. Tuchin "Measurement of tissue optical properties in the context of tissue optical clearing," Journal of Biomedical Optics 23(9), 091416 (23 August 2018). https://doi.org/10.1117/1.JBO.23.9.091416

Received: 12 February 2018; Accepted: 30 July 2018; Published: 23 August 2018

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