Photoacoustic computed tomography of human extremities

Parker Wray; Li Lin; Peng Hu; Lihong V. Wang

doi:10.1117/1.JBO.24.2.026003

19 February 2019 Photoacoustic computed tomography of human extremities

Parker Wray, Li Lin, Peng Hu, Lihong V. Wang

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Journal of Biomedical Optics, Vol. 24, Issue 2, 026003 (February 2019). https://doi.org/10.1117/1.JBO.24.2.026003

Abstract

We present a method of imaging angiographic structures in human extremities, including hands, arms, legs, and feet, using a newly developed photoacoustic computed tomography (PACT) system. The system features deep penetration (1.8 cm in muscular tissues) with high spatial and temporal resolutions. A volumetric image is acquired within 5 to 15 s while each cross sectional image is acquired within 100 μs. Therefore, we see no blurring from motion in the imaging plane. Longitudinal and latitudinal cross-sectional images of a healthy volunteer clearly show the vascular network of each appendage and highlight the system’s ability to image major and minor vasculatures, without the use of an external contrast or ionizing radiation. We also track heartbeat-induced arterial movement at a two-dimensional frame rate of 10 Hz. This work substantiates the idea that PACT could be used as a noninvasive method for imaging human vasculatures.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Parker Wray, Li Lin, Peng Hu, and Lihong V. Wang "Photoacoustic computed tomography of human extremities," Journal of Biomedical Optics 24(2), 026003 (19 February 2019). https://doi.org/10.1117/1.JBO.24.2.026003

Received: 24 July 2018; Accepted: 29 January 2019; Published: 19 February 2019

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