Open Access
22 October 2022 Interferometric diffuse optics: recent advances and future outlook
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Abstract

The field of diffuse optics has provided a rich set of neurophotonic tools to measure the human brain noninvasively. Interferometric detection is a recent, exciting methodological development in this field. The approach is especially promising for the measurement of diffuse fluctuation signals related to blood flow. Benefitting from inexpensive sensor arrays, the interferometric approach has already dramatically improved throughput, enabling the measurement of brain blood flow faster and deeper. The interferometric approach can also achieve time-of-flight resolution, improving the accuracy of acquired signals. We provide a historical perspective and summary of recent work in the nascent area of interferometric diffuse optics. We predict that the convergence of interferometric technology with existing economies of scale will propel many advances in the years to come.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
Wenjun Zhou, Mingjun Zhao, and Vivek J. Srinivasan "Interferometric diffuse optics: recent advances and future outlook," Neurophotonics 10(1), 013502 (22 October 2022). https://doi.org/10.1117/1.NPh.10.1.013502
Received: 15 July 2022; Accepted: 26 September 2022; Published: 22 October 2022
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CITATIONS
Cited by 7 scholarly publications.
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KEYWORDS
Interferometry

Heterodyning

Signal to noise ratio

Brain

Diffuse optical imaging

Homodyne detection

Cameras

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