Escherichia coli is responsible for infections in the community and in hospital settings. Photodynamic inactivation (PDI) is an alternative for the treatment of E. coli infections. However, the internalization of photosensitizers (PS), a key element for PDI efficient performance, is still not fully understood. Here, we evaluated thermal and temporal effects on PS uptake in E. coli suspensions. PS internalization estimates were performed by UV-visible absorption spectroscopy and showed influences of temperature and time in PS internalization. We believe that finding ideal conditions for PS uptake in E. coli can improve the PDI process.
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