Mr. Cody F. Bahavar Profile

Cody F. Bahavar

Research Assistant at Univ of Central Oklahoma

SPIE Involvement:

Author

Proceedings Article | 21 March 2016 Presentation + Paper

Comparison of the photothermal effects of 808nm gold nanorod and indocyanine green solutions using an 805nm diode laser

Aamr Hasanjee, Feifan Zhou, Connor West, Kegan Silk, Austin Doughty, Cody Bahavar, Wei Chen

Proceedings Volume 9709, 97090A (2016) https://doi.org/10.1117/12.2214631

KEYWORDS: Gold, Indocyanine green, Semiconductor lasers, Laser irradiation, Photothermal effect, Cancer, Absorption, Single walled carbon nanotubes, Nanorods, Tumors

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Proceedings Article | 10 March 2016 Paper

The effects of laser immunotherapy on cancer cell migration

Cody Bahavar, Feifan Zhou, Aamr Hasanjee, Elivia Layton, Anh Lam, Wei Chen, Melville Vaughan

Proceedings Volume 9709, 97090X (2016) https://doi.org/10.1117/12.2216592

KEYWORDS: Laser irradiation, Cancer, Single walled carbon nanotubes, In vitro testing, Resistance, Optical properties, In vivo imaging, Tumors, Biomedical optics, Medical research, Biology

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Proceedings Article | 9 March 2016 Presentation + Paper

Clinical effects of laser immunotherapy on metastatic cancer patients

Mark Naylor, Anh Lam, Cody Bahavar, Robert Nordquist, Wei Chen

Proceedings Volume 9709, 97090H (2016) https://doi.org/10.1117/12.2213891

KEYWORDS: Cancer, Melanoma, Laser therapeutics, Photoimmunotherapy, Breast cancer, Oncology, Diagnostics and therapeutics, Tumors, Computed tomography, Radiotherapy, Lithium, Lung

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Proceedings Article | 9 March 2015 Paper

The immunological response created by interstitial and non-invasive laser immunotherapy

Cody Bahavar, Feifan Zhou, Aamr Hasanjee, Connor West, Robert Nordquist, Tomas Hode, Hong Liu, Wei Chen

Proceedings Volume 9324, 93240D (2015) https://doi.org/10.1117/12.2082658

KEYWORDS: Tumors, Laser irradiation, Single walled carbon nanotubes, Cancer, Skin, Biomedical optics, Clinical trials, Breast cancer, Melanoma, Carbon nanotubes

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Laser immunotherapy (LIT) is an innovative cancer modality that uses laser irradiation and immunological stimulation to treat late-stage, metastatic cancers. LIT can be performed through either interstitial or non-invasive laser irradiation. Although LIT is still in development, recent clinical trials have shown that it can be used to successfully treat patients with late-stage breast cancer and melanoma. The development of LIT has been focused on creating an optimal immune response created by irradiating the tumor. One important factor that could enhance the immune response is the duration of laser irradiation. Irradiating the tumor for a shorter or longer amount of time could weaken the immune response created by LIT. Another factor that could weaken this immune response is the proliferation of regulatory T cells (TRegs) in response to the laser irradiation. However, low dose cyclophosphamide (CY) can help suppress the proliferation of TRegs and help create a more optimal immune response. An additional factor that could weaken the effectiveness of LIT is the selectivity of the laser. If LIT is performed non-invasively, then deeply embedded tumors and highly pigmented skin could cause an uneven temperature distribution inside the tumor. To solve this problem, an immunologically modified carbon nanotube system was created by using an immunoadjuvant known as glycated chitosan (GC) as a surfactant for single-walled carbon nanotubes (SWNTs) to immunologically modify SWNTs. SWNT-GC retains the optical properties of SWNTs and the immunological functions of GC to help increase the selectivity of the laser and create a more optimal immune response. In this preliminary study, tumor-bearing rats were treated with LIT either interstitially by an 805-nm laser with GC and low-dose CY, or non-invasively by a 980-nm laser with SWNT-GC. The goal was to observe the effects of CY on the immune response induced by LIT and to also determine the effect of irradiation duration for interstitial and noninvasive LIT.

Proceedings Article | 9 March 2015 Paper

Anti-tumor response induced by immunologically modified carbon nanotubes and laser irradiation using rat mammary tumor model

Joseph Acquaviva, Aamr Hasanjee, Cody Bahavar, Fefian Zhou, Hong Liu, Eric Howard, Liz Bullen, Ricardo Silvy, Wei Chen

Proceedings Volume 9324, 932415 (2015) https://doi.org/10.1117/12.2080890

KEYWORDS: Tumors, Single walled carbon nanotubes, Laser irradiation, Cancer, Carbon nanotubes, Cell death, Oncology, Magnesium, Biomedical optics, Nanotechnology

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Proceedings Article | 27 February 2014 Paper

Laser assisted immunotherapy (LIT) for chemotherapy-resistant neoplasms: recent case reports

Robert Nordquist, Cody Bahavar, Feifan Zhou, Tomas Hode, Wei Chen, Xiaosong Li, Mark Naylor

Proceedings Volume 8944, 894406 (2014) https://doi.org/10.1117/12.2041646

KEYWORDS: Tumors, Melanoma, Therapeutics, Laser therapeutics, Solids, Breast cancer, Fiber lasers, Chest, Breast, Computed tomography

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Proceedings Article | 27 February 2014 Paper

Effects of cyclophosphamide on laser immunotherapy for the treatment of metastatic cancer

Cody Bahavar, Joseph Acquaviva, Sheyla Rabei, Allie Sikes, Robert Nordquist, Tomas Hode, Hong Liu, Wei Chen

Proceedings Volume 8944, 894408 (2014) https://doi.org/10.1117/12.2040954

KEYWORDS: Tumors, Cancer, Laser irradiation, Oncology, Biomedical optics, Clinical trials, Breast cancer, Melanoma, Fiber lasers, Optical fibers

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Proceedings Article | 22 February 2013 Paper

Effects of interstitial laser immunotherapy for the treatment of metastatic cancer

Cody Bahavar, Jessica Goddard, Allie Sikes, Ellen Boarman, Robert Nordquist, Tomas Hode, Hong Liu, Wei Chen

Proceedings Volume 8582, 858207 (2013) https://doi.org/10.1117/12.2006462

KEYWORDS: Tumors, Laser irradiation, Cancer, Oncology, Laser tissue interaction, Skin, Tissues, Magnetic resonance imaging, Temperature metrology, Diffusers

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Showing 5 of 8 publications

Conference Committee Involvement (1)

Biophotonics and Immune Responses IX

1 February 2014 |

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