We present a study on diopside nanotracers with persistent luminescence properties in the red-near IR range for small animal imaging. In this paper we have focused our attention on improving the persistent luminescence of diopside nanoparticles doped with transition metal and lanthanide ions. Earlier study showed that Pr3+ is the most suitable Ln3+ electron trap in Eu2+, Mn 2+ doped diopside lattice. Here, we report an optimization of both chemical composition of CaMgSi2O6 matrix and Eu, Mn, Pr doping elements to improve persistent luminescence. These new inorganic persistent luminescent nanoparticles (i-PLNPs) emit in the red-near infrared range for several hours and can master the difficulties due to the biological environment.
We present a new generation of nanotracers with persistent luminescence properties in the red-near IR range for small animal imaging. Silicates, oxysulfides and calcium phosphates nanoparticles doped with transition metal and lanthanide ions were developed in this aim. We have focused our attention in this paper on the biocompatible TCP/HAp phosphate compounds doped with Eu, Mn, Dy and on the Gd2O2S:Eu, Mg, Ti materials in the form of nanoparticles. All the nanosensors were hydrothermally synthesized and if the phosphate has a very high interest due to its biocompatibility Gd2O2S:Eu, Mg, Ti was investigated as a multimodal agent for possible in vivo optical imaging and MRI imaging.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.