Dr. Elizabeth Tai Profile

Dr. Elizabeth Tai

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 29 March 2024 Presentation + Paper

Modular 3D-printed liver tumour phantom for modelling embolization procedures

David Ng, Hristo Nikolov, Elizabeth Tai, Daniel Gelman, David Holdsworth, Maria Drangova

Proceedings Volume 12928, 129281E (2024) https://doi.org/10.1117/12.3004837

KEYWORDS: 3D modeling, 3D printing, Angiography, Liver, Resistance, Radiography, Arteries, Modeling, Mixtures, Contrast agents

Read Abstract +

Angiographic evaluation is important in embolization procedures to ensure a proper amount of embolic material is delivered to target vessels. Simulation of image-guided interventions with phantoms enables scientists and residents to better understand techniques to avoid procedure-related complications. In this study, a phantom with an exchangeable, single-use tumour model was designed and fabricated using 3D-printing in polylactic acid plastic. A 1.5 cm sphere made of gyroids with varying pore sizes was used in place of tubular structures to simulate tumour microvasculature and thereby provide restrictive passages that trap embolic material. Hemodynamic blood properties were replicated using a pulsatile flow pump containing a glycerol-water mixture and flow resistance was mimicked by adding tubing to each outlet vessel. Tissue-mimicking material was introduced around the phantom to provide radiographic path equalization. The modular phantom was used to mimic fluoroscopically guided embolization procedures in three tumour models, culminating in reflux observed in the feeding artery. Angiography revealed a tumour blush created by the gyroid patterns. Embolization of the tumour model proceeded gradually with contrast agent accumulating in the tumour over time where reflux developed after injecting 5.4 ± 2.4 mL of a microsphere/contrast mixture. The pulsatility of the blood-mimicking fluid was clearly seen when contrast agent was injected. Digital subtraction angiography after embolization revealed complete stasis of antegrade flow through the tumour model. The 3D printed modular phantom design facilitates the reusability of the liver model following embolization, allowing for a more efficient and versatile tool for embolization training and research applications.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years