Laser and plasma-based techniques have been demonstrated to be effective for obtaining surfaces with functional properties i.e. adherent or repellent to different types of cells. Two Photon Polymerization-Direct Writing (2PP-DW) allowed obtaining complex hierarchical structures: a first level consisted of micrometric mushroom-like constructs, and in the second level, the mushrooms' hats were "decorated" with micro- and nanostructures in the shape of elliptical ripple-like patterns. Their wettability was found to strongly depends on the morphology aspect ratio and dimensions. Also, Matrix Assisted Pulsed Laser Evaporation of Polyvinyl formal (Formvar) - PVF allowed obtaining functional coatings with tunable adherence properties (hydrophobic/hydrophilic), depending on the experimental deposition parameters. The irradiation of ns-laser processed Polyethylene terephthalate (PET) with ripples using a cold atmospheric pressure radio frequency plasma source shown controlled changes of the surface functionality.
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