Dr. Jean-Pierre Ballini Profile

Dr. Jean-Pierre Ballini

at EPFL

SPIE Involvement:

Author

Publications (9)

SPIE Journal Paper | 22 November 2012 Open Access

Reflectance imaging of the human retina at 810 nm does not suffice to optimize the parameters of hydrodynamic rebalancing laser treatment

Filippo Piffaretti, Jean-Pierre Ballini, Roberto Perotti, Matthieu Zellweger, Edoardo Vezzola, Michel Sickenberg, Georges Wagnières

JBO, Vol. 17, Issue 11, 116027, (November 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.11.116027

KEYWORDS: Reflectivity, Retina, Laser therapeutics, Eye, Laser tissue interaction, Tissues, Absorption, Optical filters, Infrared imaging, Pathology

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Proceedings Article | 13 July 2009 Paper

Vascular effects induced by anti-VEGF agents in the CAM model: effect of the DMSO

Patrycja Nowak-Sliwinska, Jean-Pierre Ballini, Hubert van den Bergh, Georges Wagnières

Proceedings Volume 7380, 73803W (2009) https://doi.org/10.1117/12.822967

KEYWORDS: Content addressable memory, Capillaries, Luminescence, Image processing, Microscopes, Tissues, Image segmentation, In vivo imaging, Image analysis, Cameras

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SPIE Journal Paper | 1 March 2009 Open Access

In vivo time-resolved spectroscopy of the human bronchial early cancer autofluorescence

Pascal Uehlinger, Tanja Gabrecht, Thomas Glanzmann, Jean-Pierre Ballini, Alexandre Radu, Snezana Andrejevic, Philippe Monnier, Georges Wagnieres

JBO, Vol. 14, Issue 02, 024011, (March 2009) https://doi.org/10.1117/12.10.1117/1.3088100

KEYWORDS: Atrial fibrillation, Luminescence, In vivo imaging, Cancer, Time resolved spectroscopy, Photonics, Bronchoscopy, Imaging systems, Tissues, Endoscopy

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Proceedings Article | 31 October 2001 Paper

Time-resolved autofluorescence spectroscopy of the bronchial mucosa for the detection of early cancer: clinical results

Thomas Glanzmann, Pascal Uehlinger, Jean-Pierre Ballini, Alexandre Radu, Tanja Gabrecht, Philippe Monnier, Hubert van den Bergh, Georges Wagnieres

Proceedings Volume 4432, (2001) https://doi.org/10.1117/12.447136

KEYWORDS: Luminescence, Tissues, Tissue optics, Endoscopy, Imaging devices, Optical fibers, Optical testing, Spectroscopy, Time resolved spectroscopy, Auto-fluorescence imaging

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Proceedings Article | 6 December 1996 Paper

Design and characterization of a phantom that simultaneously simulates tissue optical properties between 400 and 650 nm

Georges Wagnieres, Shangguan Cheng, Matthieu Zellweger, Nora Doegnitz-Utke, Daniel Braichotte, Jean-Pierre Ballini, Hubert van den Bergh

Proceedings Volume 2926, (1996) https://doi.org/10.1117/12.260824

KEYWORDS: Tissues, Optical properties, Luminescence, Absorption, Tissue optics, Scattering, Blood, Monte Carlo methods, Ruby, Silica

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Proceedings Article | 6 December 1996 Paper

Tissue characterization by time-resolved fluorescence spectroscopy of endogenous and exogenous fluorochromes: apparatus design and preliminary results

Thomas Glanzmann, Jean-Pierre Ballini, Patrice Jichlinski, Hubert van den Bergh, Georges Wagnieres

Proceedings Volume 2926, (1996) https://doi.org/10.1117/12.260818

KEYWORDS: Luminescence, Tissues, Tissue optics, Bladder, Time resolved spectroscopy, Dye lasers, Fluorescence spectroscopy, Argon ion lasers, Tumors, Spectroscopy

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Proceedings Article | 17 June 1993 Paper

Optical laser microspectroscopies within single living cells

Laurent Chinsky, M. Duquesne, A. Laigle, F. Sureau, Pierre-Yves Turpin, C. Amirand, Jean-Pierre Ballini, Paul Vigny

Proceedings Volume 1922, (1993) https://doi.org/10.1117/12.146187

KEYWORDS: Laser optics, Imaging spectroscopy, Luminescence, Raman spectroscopy, Microscopes, Calcium, Spectroscopy, Visible radiation, Molecules, Ultraviolet radiation

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Proceedings Article | 1 May 1991 Paper

High-power UV laser photolysis of nucleosides: final product analysis

Dimitar Angelov, M. Berger, J. Cadet, Jean-Pierre Ballini, E. Keskinova, Paul Vigny

Proceedings Volume 1403, (1991) https://doi.org/10.1117/12.57289

KEYWORDS: Photolysis, Chemistry, High power lasers, Ultraviolet radiation, Electroluminescence, Temperature metrology, Mass spectrometry, Chromatography, Picosecond phenomena, Photochemistry

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Proceedings Article | 1 May 1990 Paper

Time-resolved spectroscopy of the intrinsic fluorescence of nucleic acid species

Malcolm Daniels, Lucas Hart, Paul Ho, Jean-Pierre Ballini, Paul Vigny

Proceedings Volume 1204, (1990) https://doi.org/10.1117/12.17696

KEYWORDS: Absorption, Luminescence, Picosecond phenomena, Chromophores, Synchrotrons, Time resolved spectroscopy, Biochemistry, Signal detection, Crystals, Oscillators

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Polarization and lifetime studies have shown that the fluorescence from nucleic acid species is complex, both at the individual chromophore level and because of the effect of stacking interactions on the electronic states. Recent work aimed at elucidating some aspects of this behavior by decay analysis and time-resolved spectroscopy is surveyed. Experimental work has been carried out using the ACO synchrotron at LURE (France) with time-correlated single photon counting, or a frequency-doubled N2-pumped dye laser, pulse width 700 ps, with fast-gated (100 ps width) analog detection and signal averaging. Decay curves are treated by global analysis using the Marquardt non-linear least-squares algorithm (synchrotron data) or the SPLMOD program (EMBO), which carries out a non-linear leastsquares minimization using cubic splines, for the laser data. Resolution of the decay data gives a model-based estimate of the number of components and their lifetimes. This information is then used to deconvolute timewindowed spectra (time-delayed spectra) into the time-resolved spectra. It is a particular feature of the combination of delayed photon counting with the continuous wavelength distribution of pulsed synchrotron radiation that excitation spectra correlating with emissions of different lifetimes can be obtained by uninterrupted repetitive scanning over a wide range of exciting wavelengths, in the present work from 230 nm to 354 urn. Such time-delayed excitation spectra can also be deconvoluted into components corresponding to the various time-resolved emission spectra. Examples of these three types of information viz resolved lifetimes, time-resolved emission spectra and their excitation spectra are presented and discussed for the following systems. I. adenosine; 6N, 6N-dimethyladenosine; protonated adenosine; this work shows the role of rotamers in the excited state behavior of this chromophore and demonstrates the forbidden nature of the lowest excited state. II. d(AT); d(TA); we observe the sequence dependence of emission from the stacked state which has been observed previously in polarization studies and an unusual excitation spectrum. III. d(CG); poly d(CG), "B"-DNA structure; single crystal duplex d(CG)3, "Z"-DNA structure. Distinctive differences are observed between the stacked emissions from the "B" and "Z" structures which we attribute to different overlapping of the stacked bases.

Showing 5 of 9 publications

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