Microstructured optical fibers (MOF) are a highly efficient support for the design and construction of sensitive and lowcost sensors. Currently, molecular imprinting is one of the promising method of MOF inner surface functionalization. Molecularly imprinted polymers (MIP) can be synthesized at MOF inner surface and intensify the selectivity and efficiency of target molecules sorption. This approach can be the base for selective sorption and detection of target molecules on a single sensor device. This paper describes MOF modification by MIP selective for bovine serum albumin (BSA). Polyaniline was used as matrix MIP polymer and was obtained by chemical oxidate polymerization of aniline in soft acid conditions. MOF transmission spectrum were used for monitoring of bonding between the protein molecules and MIP.
Alloyed quantum dots (QDs) are the popular material for the fabrication of the light-emitting diodes because of their optical parameters advantages. One of the most interesting features peculiar to this QDs class is the ability to controlled size-independent emission peak tuning via compound amounts changing. The same advantages can be valuable in bioanalytical methods and sensor systems development. Facile one-pot synthesis of the bright quaternary alloyed QDs made by CdxZn1-xSeyS1-y/ZnS semiconductor composition with narrow (FWHM < 26 nm) emission peak (548 nm) and photoluminescence quantum yield (PLQY) up to 50% was described. Obtained QDs were stabilized in water by the dihydrolipoic acid (DHLA) ligand exchange approach with insignificant PLQY loss relative initial (16%) and great colloidal stability period (6 months). This article summarizes the easiest ways of the alloyed QDs synthesis and subsequent hydrophilization for the potential simplification of their large-amounts manufacturing procedure.
One of the most interesting modern platforms for fiber-optic biosensor are microstructured optical fibers. The analytical signal in label-free analysis can be determined by the following mechanisms: changes in the thickness of biomolecule layers immobilized on the surface of the fiber hollow fiber core; small changes in the refractive index of the analyzed solution in the fiber hollow core of the fiber and the absorption spectrum of the analyzed solution. In this article, we report data on the effect of different salt solutions small concentration changes on the MOF HC transmission spectra
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