The results of research of samples of distal femoral epiphysis in rabbits that had different types of plasty using the Raman spectroscopy method are presented. The component analysis of the samples under study has been made using spectra deconvolution by spectral contour selection The efficiency of the method of treatment of cartilage destruction using the combination of platelet-rich plasma with a bone is shown. It has been established that Raman spectroscopy can be used for estimation of areas of articular surface after chondroplasty and of degree of cartilage recovery.
This paper presents a spectral analysis of various zones of the surfaces of bone and cartilaginous regenerates using the Raman spectroscopy method combined with surface scanning using a stepper motor. It was established that the regenerates at the studied stages of development and the cartilage zone have a similar composition of the relative content of GAG and amides. It indicates a good regenerative potentia.
The paper presents the results of a comparative analysis by the method of Raman spectroscopy of the joint hyaline cartilage of adults and children. Differences in the spectral characteristics of the surface of articular cartilage are shown. New optical coefficients have been introduced, which make it possible to evaluate the age-related changes in cartilaginous tissue.
The work presents the results of studies of samples of human articular surface of the knee joint, obtained by Raman spectroscopy implementedduring endoprosthesis replacement surgery . The main spectral characteristics of articular surface areas with varying degrees of cartilage damage were detected at 956 cm-1, 1066 cm-1 wavenumbers, corresponding to phosphate and carbonate, and at 1660 cm-1, 1271 cm-1 wavenumbers, corresponding to amide I and amide III. Criteria allowing to identify the degree of articular hyaline cartilage damage were introduced.
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