Dr. Yuri N. Zakharov Profile

Dr. Yuri N. Zakharov

Lecturer at Beth Israel Deaconess Medical Ctr

SPIE Involvement:

Author

Publications (19)

Proceedings Article | 12 March 2024 Presentation + Paper

Endoscopic light scattering spectroscopy for in vivo detection of pre-cancer in bile duct

Le Qiu, Douglas Pleskow, Mandeep Sawhney, Paul Upputuri, Tyler Berzin, Mark Coughlan, Umar Khan, Xuejun Zhang, Jonah Cohen, Yuri Zakharov, Lei Zhang, Lev Perelman

Proceedings Volume 12856, 1285603 (2024) https://doi.org/10.1117/12.2692402

KEYWORDS: Cancer detection, Diagnostics, Scattering, In vivo imaging, Backscatter, Tissues, Spectroscopy, Light scattering, Endoscopy, Cancer

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Proceedings Article | 9 August 2023 Paper

C-CLASS microscopy allows the detection of nanoscale changes in chromatin structure

Mark Coughlan, Giuseppe Pettinato, Maria Glyavina, Xuejun Zhang, Liming Chen, Umar Khan, Paul Upputuri, Yuri Zakharov, Lei Zhang, Le Qiu, Lev Perelman

Proceedings Volume 12630, 126300U (2023) https://doi.org/10.1117/12.2667044

KEYWORDS: Light scattering, Spectroscopy, Confocal microscopy, Imaging spectroscopy

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Proceedings Article | 3 March 2022 Paper

A portable light scattering system for detecting expelled droplets to assess Covid-19 transmission risk

Mark Coughlan, Mandeep Sawhney, Douglas Pleskow, Tyler Berzin, Umar Khan, Maria Glyavina, Xuejun Zhang, Liming Chen, Paul Upputuri, Conor Sheil, Mohammad Bilal, Joseph Feuerstein, Andy Silva-Santisteban, Yuri Zakharov, Edward Vitkin, Irving Itzkan, Lei Zhang, Le Qiu, Lev Perelman

Proceedings Volume 11974, 1197406 (2022) https://doi.org/10.1117/12.2608902

KEYWORDS: Scattering, Light scattering, Particles, Cameras, Visualization, Sensors, Imaging systems, Endoscopy, Computer aided design, Aerosols

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Proceedings Article | 3 March 2022 Presentation

Spectroscopic label-free light scattering microscopy of chromatin organization and dynamics in live cells

Mark Coughlan, Maria Glyavina, Giuseppe Pettinato, Yuri Zakharov, Xuejun Zhang, Umar Khan, Liming Chen, Paul Upputuri, Edward Vitkin, Irving Itzkan, Lei Zhang, Le Qiu, Lev Perelman

Proceedings Volume PC11974, PC1197408 (2022) https://doi.org/10.1117/12.2608948

KEYWORDS: Light scattering, Spectroscopy, Microscopy, Confocal microscopy, Genomics, Diffraction, Structural dynamics, Scattering, Natural surfaces, Nanotechnology

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Proceedings Article | 5 March 2021 Presentation

Imaging and spectroscopy with scattered light from the tissue to chromatin scale

Mark Coughlan, Maria Glyavina, Xuejun Zhang, Umar Khan, Yuri Zakharov, Edward Vitkin, Lei Zhang, Irving Itzkan, Douglas Pleskow, Le Qiu, Lev Perelman

Proceedings Volume 11622, 116220D (2021) https://doi.org/10.1117/12.2590876

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Proceedings Article | 13 March 2019 Presentation

Holographic scanning microscope: simulation of hologram recording and wavefront reconstruction (Conference Presentation)

Maria Muravyeva, Yuri Zakharov

Proceedings Volume 10944, 109440K (2019) https://doi.org/10.1117/12.2508926

KEYWORDS: Holograms, Holography, Microscopes, Optical simulations, Wavefronts, Reconstruction algorithms, Confocal microscopy, Microscopy, Optical design, Laser scanners

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Proceedings Article | 17 July 2015 Paper

Possibilities of holographic techniques in laser scanning microscopy

Yu. Zakharov, M. Muravyeva, V. Dudenkova, I. Mukhina, I. Meglinski

Proceedings Volume 9540, 95400P (2015) https://doi.org/10.1117/12.2183814

KEYWORDS: Microscopy, Digital holography, Holograms, Confocal microscopy, Holography, Laser scanners, Microscopes, Mirrors, Biomedical optics, Computed tomography

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Proceedings Article | 22 June 2015 Paper

Superresolution imaging system on innovative localization microscopy technique with commonly using dyes and CMOS camera

V. Dudenkova, Yu. Zakharov

Proceedings Volume 9529, 95290V (2015) https://doi.org/10.1117/12.2184535

KEYWORDS: Molecules, Microscopy, Image resolution, Super resolution, CMOS cameras, Diffraction, Cameras, Tissue optics, Imaging systems, Biomedical optics

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Proceedings Article | 22 April 2008 Paper

Semiconductor laser's on-line coherence calibration and testing of frequency stability

Yu. Zakharov, A. Yu. Popov, A. Tyurin

Proceedings Volume 7008, 70081P (2008) https://doi.org/10.1117/12.797111

KEYWORDS: Semiconductor lasers, Modulation, Speckle, Holography, Interferometry, Phase interferometry, Speckle interferometry, Holograms, Calibration, Visibility

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One of the main constituent parts of optical coherent measuring apparatus is laser as source with stable performance of frequency, radiation intensity, and light beam uniformity. At present time semiconductor lasers are rather attractive devices in view of there low prices, small size, serviceability. Progress in its quality leads to including them not only in lightheads, but as lighting unit in measuring apparatus. In order to guarantee accuracy of measuring instruments, all parts of them must have stable performance, and in this respect semiconductor laser demand stabilization more that one characteristic quantity at once. And frequency stability on the one hand is overwhelmingly important for constancy of optical measuring instruments, on the other hand our investigations show that its regulatory control is very arduous task. Both holographic methods and phase modulated speckle interferometry clearly recognize smooth frequency shift and frequency jumping depending on pumping current and temperature. And for repeatability it's required to return both of them. So it is necessary laser frequency testing during working. For interferometric comparison circuit it is frequency variation that exerts influence on fringes pattern generation, so just this parameter should be traced in the course of measuring. Specially prepared test object, introduced in holographic scheme, allows to uncover frequency variation, if they had have place, and to reproduce coherence function of laser source. Complicated coherence function of semiconductor lasers can destroy interference pattern or foul the interpretation of it. So this coherence calibration is also very useful for results validity. Phase modulated speckle interferometry method allows to build phase correlation portraits, analogical to interferograms, hence multiwavelength contour generation masks the picture of intrinsic object information too. Both real wavelength change and nonresolution area, when coherence length is less then path-length difference, may be obtained with the help of known wedge incline near the measured object. Since measured and testing image will be entered at the same time, test results will be applied in interpretation of measurement results. Thus on-line testing of laser characteristic quantities allows using unstable sources and increasing of measurement precision.

Proceedings Article | 14 June 2006 Paper

Lippmann-Bragg holography as a tool for mode structure measurements

Yuri Zakharov

Proceedings Volume 6254, 625417 (2006) https://doi.org/10.1117/12.679942

KEYWORDS: Holography, 3D image reconstruction, Semiconductor lasers, Holograms, Coherence (optics), Spatial coherence, Visibility, Wavefronts, Image analysis, Light sources

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Proceedings Article | 26 September 2003 Paper

Volumetric image creation with the help of interferometric structures

Yuri Zakharov, Evsey Yakubovich, Pavel Khandokhin

Proceedings Volume 5134, (2003) https://doi.org/10.1117/12.518228

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Proceedings Article | 5 February 2002 Paper

Object field correlation properties as information carriers of image

Yuri Zakharov, Evsey Yakubovich, P. Khandokhin

Proceedings Volume 4607, (2002) https://doi.org/10.1117/12.455182

KEYWORDS: Eye, Lamps, Mirrors, Fizeau interferometers, 3D image reconstruction, Wavefronts, Modulation, Image registration, 3D image processing, Dielectric polarization

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Proceedings Article | 18 November 1999 Paper

Multibeam Fizeau interferometer pattern localization

Yuri Zakharov

Proceedings Volume 3904, (1999) https://doi.org/10.1117/12.370411

KEYWORDS: Mirrors, Fizeau interferometers, Wave propagation interference, Refraction, Interferometers, Laser interferometry, Spectroscopy, Optical testing, Optical properties, Beam shaping

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Proceedings Article | 19 July 1999 Paper

Multibeam Fizeau interferometer image plane

Yuri Zakharov

Proceedings Volume 3749, (1999) https://doi.org/10.1117/12.355010

KEYWORDS: Mirrors, Fizeau interferometers, Wave propagation interference, Interferometers, Refraction, Signal processing, Image processing, Color vision, Interferometry, Spectroscopy

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Proceedings Article | 1 December 1997 Paper

Laser setup for production of holographic portraits (Abstract Only)

Yuri Zakharov

Proceedings Volume 3317, (1997) https://doi.org/10.1117/12.295679

KEYWORDS: Holography, Holograms, Nondestructive evaluation, Optical design, Ruby lasers, Laser development, Fabry–Perot interferometers, Q switched lasers, Ruby, Neodymium

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Proceedings Article | 1 December 1997 Paper

Fabry-Perot interferometer application features in moving-target holography

Yuri Zakharov

Proceedings Volume 3317, (1997) https://doi.org/10.1117/12.295680

KEYWORDS: Holography, Fabry–Perot interferometry, Lenses, Fluctuations and noise, Mirrors, Fourier transforms, Convolution, Holograms, Fabry–Perot interferometers, Spectroscopy

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Proceedings Article | 10 November 1995 Paper

Testing of relief with the submicron accuracy by Lippmann-Bragg holography

Yuri Zakharov

Proceedings Volume 2647, (1995) https://doi.org/10.1117/12.226698

KEYWORDS: Holograms, Holography, 3D image reconstruction, Ruby lasers, 3D image processing, Reflection, Ruby, Fabry–Perot interferometers, Volume holography, Geometrical optics

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Proceedings Article | 10 December 1993 Paper

Solid state tunable laser for space-and-time-domain holography

A. Babin, Felix Feldchtein, A. Kiselev, Alexey Korytin, Alexander Sergeev, Yuri Zakharov

Proceedings Volume 2108, (1993) https://doi.org/10.1117/12.165406

KEYWORDS: Holography, Solid state lasers, Solid state physics, Tunable lasers, 3D image processing, Femtosecond phenomena, Holograms, Data storage, Image processing, Optical resolution

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Proceedings Article | 10 December 1993 Paper

Holographic testing of relief with submicron accuracy

Yuri Zakharov

Proceedings Volume 2108, (1993) https://doi.org/10.1117/12.165405

KEYWORDS: Holograms, Holography, Ruby lasers, Holographic testing, Fabry–Perot interferometers, Argon, Mirrors, 3D image reconstruction, Wave plates, Data storage

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Showing 5 of 19 publications

Proceedings Volume Editor (1)

SPIE Conference Volume | 26 September 2003

Current Research on Holography and Interferometric Methods for Measurement of Object Properties: 2000-2002

Conference Committee Involvement (1)

Current Research on Holography and Interferometric Methods for Measurement of Object Properties: 2000-2002

1 January 2000 | Unknown, United States

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