Propagation-based and mesh-based x-ray quantitative phase imaging with conventional sources

Weiyuan Sun; Carolyn A. MacDonald; Jonathan C. Petruccelli

doi:10.1117/12.2520756

13 May 2019 Propagation-based and mesh-based x-ray quantitative phase imaging with conventional sources

Weiyuan Sun, Carolyn A. MacDonald, Jonathan C. Petruccelli

Proceedings Volume 10990, Computational Imaging IV; 109900U (2019) https://doi.org/10.1117/12.2520756
Event: SPIE Defense + Commercial Sensing, 2019, Baltimore, MD, United States

Abstract

The contrast in conventional x-ray imaging is generated by differential attenuation of x rays, which is generally very small in soft tissue. Phase imaging has been shown to improve contrast and signal to noise ratio (SNR) by factors of 100 or more. However, acquiring phase images typically requires a highly spatially coherent source (e.g. a 50 μm or smaller microfocus source or a synchrotron facility), or multiple images acquired with precisely aligned gratings. Here we demonstrate two phase imaging techniques compatible with conventional sources: polycapillary focusing optics to enhance source coherence and mesh-based structured illumination.

Conference Presentation

Citation Download Citation

Weiyuan Sun, Carolyn A. MacDonald, and Jonathan C. Petruccelli "Propagation-based and mesh-based x-ray quantitative phase imaging with conventional sources", Proc. SPIE 10990, Computational Imaging IV, 109900U (13 May 2019); https://doi.org/10.1117/12.2520756

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