Imaging  the intracellular motion of the urothelium with OCT

Zhuo Xu; Hui Wang

doi:10.1117/12.2578825

5 March 2021 Imaging the intracellular motion of the urothelium with OCT

Zhuo Xu, Hui Wang

Proceedings Volume 11641, Dynamics and Fluctuations in Biomedical Photonics XVIII; 1164108 (2021) https://doi.org/10.1117/12.2578825
Event: SPIE BiOS, 2021, Online Only

Abstract

Intracellular motion (IM) is originated from the motion of molecules and organelles in the cytoplasm of eukaryotic cells. IM is essential for the proper functioning of cells. Instead of tracking specific molecules, coherent gated methods measure the speckle variation induced by IM. Initially, holographic optical coherence imaging was used to image the IM of tumor spheroids and drugs' responses^1,2 . Later on, with optical coherence tomography (OCT), IM has been used as an endogenous contrast to reveal the cellular and subcellular structures with freshly excised tissue. The uniqueness of the coherent gated method is that it can detect IM at different depths without requiring fluorescence tagging. Therefore, the imaged objects can stay at a more natural status.

Conference Presentation

Citation Download Citation

Zhuo Xu and Hui Wang "Imaging the intracellular motion of the urothelium with OCT", Proc. SPIE 11641, Dynamics and Fluctuations in Biomedical Photonics XVIII, 1164108 (5 March 2021); https://doi.org/10.1117/12.2578825

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available