Optical coherence tomography in diagnostics and guided surgery of bladder cancer

Elena Zagaynova; Olga Streltzova; Natalia D. Gladkova; Natalia M. Shakhova; Felix I. Feldchtein; Vladislav A. Kamensky; Grigory V. Gelikonov; Ekaterina Donchenko

doi:10.1117/12.530794

1 July 2004 Optical coherence tomography in diagnostics and guided surgery of bladder cancer

Elena Zagaynova, Olga Streltzova, Natalia D. Gladkova, Natalia M. Shakhova, Felix I. Feldchtein, Vladislav A. Kamensky, Grigory V. Gelikonov, Ekaterina Donchenko

Author Affiliations +

Proceedings Volume 5316, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII; (2004) https://doi.org/10.1117/12.530794
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

We performed blind recognition of optical coherence tomography (OCT) images of human urinary bladder for diagnostics of carcinoma and premalignant conditions. OCT images of 63 patients were acquired in vivo during cystoscopic examination. The malignant/premalignant conditions were differentiated from benign/reactive with 98% sensitivity and 72% specificity. OCT was also used for intraoperative monitoring of zones around the tumor for adequate resection (31 patients). OCT - guided planning of the resection margin and examination of the postoperative resection line after transurethral resection (TUR) was performed.

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Elena Zagaynova, Olga Streltzova, Natalia D. Gladkova, Natalia M. Shakhova, Felix I. Feldchtein, Vladislav A. Kamensky, Grigory V. Gelikonov, and Ekaterina Donchenko "Optical coherence tomography in diagnostics and guided surgery of bladder cancer", Proc. SPIE 5316, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII, (1 July 2004); https://doi.org/10.1117/12.530794

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