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5 March 2021 Measurement of equatorial sclera mechanical anisotropy of using acoustic radiation force optical coherence elastography
Fengyi Zhang, Yan Li, Yirui Zhu, Runze Li, Susannah Waxman, Qifa Zhou, Ian A. Sinal, Zhongping Chen
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Proceedings Volume 11655, Label-free Biomedical Imaging and Sensing (LBIS) 2021; 116550P (2021) https://doi.org/10.1117/12.2582833
Event: SPIE BiOS, 2021, Online Only
Abstract
Most soft tissues, such as cornea and sclera, exhibit mechanical anisotropy. Obtaining the anisotropy properties of the sclera can be helpful in understanding the mechanical properties of the eyes in the development and progression of glaucoma and myopia. In this work, we have demonstrated a method of quantifying the anisotropic Young’s modulus values for sclera, using a confocal Lamb wave based acoustic radiation force optical coherence elastography (ARF-OCE). We have measured mechanical anisotropy in porcine sclera by measuring the Young’s modulus along both the equator direction and anterior to posterior direction. The results demonstrate the Young’s modus in the equator direction is 15-30% higher than that in the anterior to posterior direction.
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Fengyi Zhang, Yan Li, Yirui Zhu, Runze Li, Susannah Waxman, Qifa Zhou, Ian A. Sinal, and Zhongping Chen "Measurement of equatorial sclera mechanical anisotropy of using acoustic radiation force optical coherence elastography", Proc. SPIE 11655, Label-free Biomedical Imaging and Sensing (LBIS) 2021, 116550P (5 March 2021); https://doi.org/10.1117/12.2582833
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KEYWORDS
Sclera
Anisotropy
Acoustics
Coherence (optics)
Elastography
Soft tissue optics
Tissue optics
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