Dr. Ian A. Sigal Profile

Dr. Ian A. Sigal

Associate Professor at Univ of Pittsburgh

SPIE Involvement:

Conference Program Committee | Author

Proceedings Article | 15 March 2023 Presentation

Characterizing femtosecond laser effects on collagen (Conference Presentation)

Po-Yi Lee, Yuankai Lu, Marissa Quinn, Susannah Waxman, Fengting Ji, Gregory Gibson, Bin Yang, Ian Sigal

Proceedings Volume PC12381, PC123810H (2023) https://doi.org/10.1117/12.2647185

KEYWORDS: Collagen, Femtosecond phenomena, Tissues, Second-harmonic generation, Imaging systems, Electrons, Two photon imaging, Tissue engineering, Signal attenuation, Polarized microscopy

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Proceedings Article | 5 March 2021 Presentation

Equatorial sclera anisotropy measured using ultrasound elastography

Runze Li, Susannah Waxman, Yi Hua, Fengyi Fengyi Zhang, Yan Li, Yirui Zhu, Xuejun Qian, Zhongping Chen, Qifa Zhou, Ian Sigal

Proceedings Volume 11645, 116450Z (2021) https://doi.org/10.1117/12.2583975

KEYWORDS: Anisotropy, Ultrasonography, Sclera, Elastography, Electroactive polymers, Eye, Wave propagation, Vitreous, Transducers, Tissues

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Proceedings Article | 5 March 2021 Presentation

Measurement of equatorial sclera mechanical anisotropy of using acoustic radiation force optical coherence elastography

Fengyi Zhang, Yan Li, Yirui Zhu, Runze Li, Susannah Waxman, Qifa Zhou, Ian Sinal, Zhongping Chen

Proceedings Volume 11655, 116550P (2021) https://doi.org/10.1117/12.2582833

KEYWORDS: Sclera, Anisotropy, Acoustics, Elastography, Coherence (optics), Tissue optics, Soft tissue optics, Tissues, Cornea, Transducers

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Proceedings Article | 5 March 2021 Presentation + Paper

Real-time structured polarized light imaging of dynamics of thick collagenous tissues

Grace Ingram, Po-Yi Lee, Benjamin Bernarding, Ian Sigal, Bin Yang

Proceedings Volume 11698, 116980A (2021) https://doi.org/10.1117/12.2577833

KEYWORDS: Tissues, Collagen, Visualization, Real time imaging, Visibility, Scattering, Projection systems, Pathophysiology, Optical tracking, Natural surfaces

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Proceedings Article | 20 February 2020 Paper

Instant polarized light microscopy for real-time wide-field visualization of collagen architecture

Po-Yi Lee, Bin Yang, Yi Hua, Bryn Brazile, Fengting Ji, Ziyi Zhu, Gosia Fryc, Ian Sigal

Proceedings Volume 11251, 112510Y (2020) https://doi.org/10.1117/12.2542878

KEYWORDS: Collagen, Polarization, Microscopy, Microscopes, Polarized microscopy, Visualization, Imaging systems, Tissues, Optic nerve

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SPIE Journal Paper | 1 October 2018 Open Access

Structured polarized light microscopy for collagen fiber structure and orientation quantification in thick ocular tissues

Bin Yang, Bryn Brazile, Ning-Jiun Jan, Yi Hua, Junchao Wei, Ian Sigal

JBO, Vol. 23, Issue 10, 106001, (October 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.10.106001

KEYWORDS: Collagen, Tissues, Structured optical fibers, Microscopy, Polarized microscopy, Visualization, Optical tracking, Scattering, Eye, Light scattering

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Proceedings Article | 22 February 2018 Paper

Structured polarized light microscopy (SPLM) for mapping collagen fiber orientation of ocular tissues

Bin Yang, Bryn Brazile, Ning-Jiun Jan, Andrew Voorhees, Ian Sigal

Proceedings Volume 10546, 105460I (2018) https://doi.org/10.1117/12.2290133

KEYWORDS: Collagen, Tissues, Optic nerve, Polarized microscopy, Microscopy, Scattering, Eye, Structured light

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Proceedings Article | 19 February 2018 Paper

Measuring in-vivo and in-situ ex-vivo the 3D deformation of the lamina cribrosa microstructure under elevated intraocular pressure

Junchao Wei, Bin Yang, Andrew Voorhees, Huong Tran, Bryn Brazile, Bo Wang, Joel Schuman, Matthew Smith, Gadi Wollstein, Ian Sigal

Proceedings Volume 10496, 1049611 (2018) https://doi.org/10.1117/12.2291243

KEYWORDS: In vivo imaging, Optical coherence tomography, Image registration, Eye, 3D metrology, 3D microstructuring, 3D image processing, Tissues, Optic nerve, Blood vessels

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Proceedings Article | 21 February 2017 Paper

Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures

H. Tran, J. Grimm, B. Wang, M. Smith, A. Gogola, S. Nelson, E. Tyler-Kabara, J. Schuman, G. Wollstein, I. Sigal

Proceedings Volume 10067, 100670B (2017) https://doi.org/10.1117/12.2257360

KEYWORDS: In vivo imaging, Optical coherence tomography, Elastography, Eye, Image analysis, Tissues, Optic nerve, Head, Detection and tracking algorithms, Image registration, Biomechanics, Digital image correlation, Image processing

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Proceedings Article | 17 February 2017 Paper

Correlation between cerebral hemodynamic and perfusion pressure changes in non-human primates

A. Ruesch, M. Smith, G. Wollstein, I. Sigal, S. Nelson, J. Kainerstorfer

Proceedings Volume 10059, 100591P (2017) https://doi.org/10.1117/12.2252550

KEYWORDS: Near infrared spectroscopy, Hemodynamics, Brain, Blood, Blood pressure, Optical spectroscopy, Spectroscopy, Blood circulation, Oxygen, Tissues, Data modeling, Blood vessels

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Showing 5 of 10 publications

Conference Committee Involvement (7)

Optical Elastography and Tissue Biomechanics XII

25 January 2025 | San Francisco, California, United States

Optical Elastography and Tissue Biomechanics XI

27 January 2024 | San Francisco, California, United States

Optical Elastography and Tissue Biomechanics X

28 January 2023 | San Francisco, California, United States

Optical Elastography and Tissue Biomechanics IX

22 January 2022 | San Francisco, California, United States

Optical Elastography and Tissue Biomechanics VIII

6 March 2021 | Online Only, California, United States

Showing 5 of 7 Conference Committees

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