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Photoacoustic microscopy (PAM) is a multiscale microscopy technique with optical absorption contrast. With tight acoustic focusing, acoustic-resolution (AR-PAM) reaches the depth of several centimeters in biological tissue, but the lateral resolution is relatively poorer than optical-resolution PAM (OR-PAM). We proposed using CycleGAN to generate new OR-PAM images from the original AR-PAM images. We prepared two AR & OR-PAM datasets from leaf phantom and mouse-ear samples. After completing the CycleGAN process, we estimated the quality comparison between the original AR-PAM and the generated OR-PAM images. Finally, the results showed the ability to obtain high spatial resolution PAM images without hardware updates.
Thanh Dat Le andChangho Lee
"Spatial resolution improvement of acoustic resolution photoacoustic microscopy using cycle-consistent GAN", Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 119600C (3 March 2022); https://doi.org/10.1117/12.2608112
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Thanh Dat Le, Changho Lee, "Spatial resolution improvement of acoustic resolution photoacoustic microscopy using cycle-consistent GAN," Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 119600C (3 March 2022); https://doi.org/10.1117/12.2608112