Quantitative and qualitative histopathological comparisons of multielectrode balloon and thermal balloon endometrial ablation

Sharon L. Thomsen M.D.; Thomas P. Ryan; Karen Kuk-Nagle; Cindi Soto; Thierry G. Vancaillie M.D.; Jose Garza-Leal

doi:10.1117/12.304335

2 April 1998 Quantitative and qualitative histopathological comparisons of multielectrode balloon and thermal balloon endometrial ablation

Sharon L. Thomsen M.D., Thomas P. Ryan, Karen Kuk-Nagle, Cindi Soto, Thierry G. Vancaillie M.D., Jose Garza-Leal

Author Affiliations +

Proceedings Volume 3249, Surgical Applications of Energy; (1998) https://doi.org/10.1117/12.304335
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

Quantitative and qualitative histopathologic techniques were used to compare the distribution, severity and depths of acute thermal lesions formed by in vivo placement of three different intracavitary thermal balloon instruments in the uteri of 19 women scheduled for hysterectomy. Thermal damage reflected by (1) Nitro Blue Tetrazolium stains separating `living' from `dead' tissues, (2) red zone formation and the (3) presence of a clear zone observed in histologic slides extended into the myometrium. One hysterectomy specimen removed 4 days after treatment showed superficial slough of the endometrium but solid, coagulation necrosis of the deeper endometrium and adjacent myometrium. The treatment effect and success of intracavitary thermal coagulation may be related to a delicate balance of complete irradiation of endometrium versus fibrous stricture and intracavitary adhesions of the uterus.

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Sharon L. Thomsen M.D., Thomas P. Ryan, Karen Kuk-Nagle, Cindi Soto, Thierry G. Vancaillie M.D., and Jose Garza-Leal "Quantitative and qualitative histopathological comparisons of multielectrode balloon and thermal balloon endometrial ablation", Proc. SPIE 3249, Surgical Applications of Energy, (2 April 1998); https://doi.org/10.1117/12.304335

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