Transillumination of breast phantoms using diffuse photon-density waves

Laure Montandon-Varoda; Daniel Salzmann; Frederic P. Bevilacqua; Christian D. Depeursinge

doi:10.1117/12.356850

15 July 1999 Transillumination of breast phantoms using diffuse photon-density waves

Laure Montandon-Varoda, Daniel Salzmann, Frederic P. Bevilacqua, Christian D. Depeursinge

Proceedings Volume 3597, Optical Tomography and Spectroscopy of Tissue III; (1999) https://doi.org/10.1117/12.356850
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

Diffuse Photon Density Waves (DPDWs) characterise photon migration through diffusive media in the frequency-domain. Theoretically, we describe DPDWs propagation using the diffraction theory based on the diffusion approximation to the transport equation. Experimentally, we study the propagation of 100 MHz-modulated DPDWs through (optical)-breast-like phantoms. The great interest of probing these phantoms lies in the fact that they contain very small optical inhomogeneities, with a diameter of 5 mm only and with inhomogeneitj^ackground absorption and scattering contrasts of 1.1,1.5,2.0 and 4.0 respectively. We show that both most contrasted inhomogeneities (in absorption and scattering) can be distinguished, while the 1.5 contrasted one is visible only in scattering. This is consistent with the measured actual accuracy of our set-up which is 0.3% in amplitude and 0.15¡ in phase. Experimental results are compared to simulations, time-domain experimental results and X-ray measurements.

Citation Download Citation

Laure Montandon-Varoda, Daniel Salzmann, Frederic P. Bevilacqua, and Christian D. Depeursinge "Transillumination of breast phantoms using diffuse photon-density waves", Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); https://doi.org/10.1117/12.356850

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