Ex-vivo and phantom fluorescence spectra of human cervical tissue

Svetlana P. Chernova; Oleg V. Kasimov; Larisa M. Kuznetsova; Tatiana E. Moskalenko; Alexander B. Pravdin

doi:10.1117/12.381505

6 April 2000 Ex-vivo and phantom fluorescence spectra of human cervical tissue

Svetlana P. Chernova, Oleg V. Kasimov, Larisa M. Kuznetsova, Tatiana E. Moskalenko, Alexander B. Pravdin

Proceedings Volume 4001, Saratov Fall Meeting '99: Optical Technologies in Biophysics and Medicine; (2000) https://doi.org/10.1117/12.381505
Event: Saratov Fall Meeting '99, 1999, Saratov, Russian Federation

Abstract

In present work, fluorescence spectra of normal cervical tissue as well as some benign lesions were obtained ex vivo with 365 +/- 20 nm and 405 +/- 30 excitation. In all case of ectopia emissions from normal area appeared more intensive than from pathological one. Intensive fluorescence with specific spectral lineshape was observed on the posttraumatic scars, the main contribution to the spectrum was attributed to collagen. On the base of phantom measurement, explanation of appearance of a weak peak at 505-515 nm in tissue fluorescence spectra was proposed.

Citation Download Citation

Svetlana P. Chernova, Oleg V. Kasimov, Larisa M. Kuznetsova, Tatiana E. Moskalenko, and Alexander B. Pravdin "Ex-vivo and phantom fluorescence spectra of human cervical tissue", Proc. SPIE 4001, Saratov Fall Meeting '99: Optical Technologies in Biophysics and Medicine, (6 April 2000); https://doi.org/10.1117/12.381505

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