Practical pathology for engineers: how to do the job right the first time

Sharon L. Thomsen M.D.

doi:10.1117/12.476635

10 June 2003 Practical pathology for engineers: how to do the job right the first time

Sharon L. Thomsen M.D.

Proceedings Volume 4954, Thermal Treatment of Tissue: Energy Delivery and Assessment II; (2003) https://doi.org/10.1117/12.476635
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

Medical device development requires a phase of instrument testing and performance validation using experimental biologic targets including cells, tissues, organs and individuals in vitro and in vivo. In this development phase, qualitative and quantitative pathologic methods can be very useful to evaluate the mechanisms of detection/effect and to map the extent and severity of device energy/tissue interactions. This paper is a general overview of the philosophical and practical aspects of 1) choosing and preparing effective collaborations with biomedical experts, 2) choosing appropriate biologic target tissues and 3) preparing the tissues to obtain optimal pathologic results.

Citation Download Citation

Sharon L. Thomsen M.D. "Practical pathology for engineers: how to do the job right the first time", Proc. SPIE 4954, Thermal Treatment of Tissue: Energy Delivery and Assessment II, (10 June 2003); https://doi.org/10.1117/12.476635

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