Modeling of light diffusion in tissues by a Monte Carlo method

Livia Sterian; Camelia Blaja; Andreea-Rodica P. Sterian; C. Dordia; Mihai C. Piscureanu

doi:10.1117/12.519583

4 November 2003 Modeling of light diffusion in tissues by a Monte Carlo method

Livia Sterian, Camelia Blaja, Andreea-Rodica P. Sterian, C. Dordia, Mihai C. Piscureanu

Proceedings Volume 5226, 12th International School on Quantum Electronics: Laser Physics and Applications; (2003) https://doi.org/10.1117/12.519583
Event: 12th International School on Quantum Electronics Laser Physics and Applications, 2002, Varna, Bulgaria

Abstract

Most of the latest achievements concerning laser energy transfer through tissues is based on transport theory instead of Maxwell equations, due to the biological tissue inhomogeneities. The diffusion model we have described takes into account several tissue layers, with different optical properties, different refractive indices at their boundaries and anisotropic scattering. The algorithm has been implemented as a function which uses as parameters the simulation data (number of photons, maximal depth, analysis radius, depth and radius resolution) and also the optical characteristics of tissue layers. Our results refer to the simulation of light propagation through a single tissue layer. We have studied the optical properties of two tissue samples, of half-infinite surface, 1 cm in depth, which were irradiated with a very thin and uniform laser beam. We computed the average values of six simulations of 1000000 photons package each, for a vertical and horizontal resolution of 100 points. For a distance from the laser beam greater than 0.1 cm, the reflectances are approximately the same, while the transmittances are significantly identical at high depths inside the tissue. Our results are in good agreement with the experimental measurements, thus showing the utility of the method for several tissue layers studies.

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Livia Sterian, Camelia Blaja, Andreea-Rodica P. Sterian, C. Dordia, and Mihai C. Piscureanu "Modeling of light diffusion in tissues by a Monte Carlo method", Proc. SPIE 5226, 12th International School on Quantum Electronics: Laser Physics and Applications, (4 November 2003); https://doi.org/10.1117/12.519583

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KEYWORDS

Tissues

Photons

Monte Carlo methods

Absorption

Scattering

Laser therapeutics

Optical properties

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